Respir Physiol. 1972 Mar;14(1 219-36. An imidazole alphastat hypothesis for vertebrate acid-base regulation: tissue carbon dioxide content and body). Aug 31, 2015. Alpha-stat hypothesis. The degree of ionisation (alpha) of the imidazole groups of histidine in intracellular proteins remains constant despite changes in. Respiration Physiology (1972) 14, 219-236; North-Holland Publishing Company, Amsterdam AN IMIDAZOLE ALPHASTAT HYPOTHESIS FOR VERTEBRATE.
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